Effect of cardura on benign prostatic hyperplasia and ejectile dysfunction
10.3760/cma.j.issn.0254-9026.2011.02.018
- VernacularTitle:甲磺酸多沙唑嗪控释片治疗良性前列腺增生及改善勃起功能的研究
- Author:
Yang LUO
;
Qiong GUO
;
Xiaoxin NAN
- Publication Type:Journal Article
- Keywords:
Prostatic hyperplasia;
Doxazosin;
Urination disorders;
Penile erection
- From:
Chinese Journal of Geriatrics
2011;30(2):150-151
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic effect of cardura on lower urinary tract symptoms (LUTS) and ejectile dystunction(ED) in men with benign prostatic hyperplasia (BPH).Methods One hundred and one cases with BPH and typical LUTS were investigated using the International Prostate Symptom Score (IPSS) and International Index of Erectile Function 5 (IIEF-5)before and after treatment. The patients were given cardura 4 mg, once a day for 8 weeks. The LUTS and ED were was analyzed after treatment. Results The IPSS was scores ( 14.3 ± 4.0) after treatment, and it was lower than before (mean scores: 19.9±6.5, t= 7.534, P＜0.001). The IIEF2-5 was(14.9±8.8)scores after treatment, and it was higher than before (mean scores: 9.5±8. 5, t = 5. 335, P＜ 0. 001 ), respectively. There was statistically significant correlation between IIEF2-5 and IPSS score (r= -0. 327, P＜0. 001 ). Various indexes were significantly improved after cardura treatment as compared with pretreatment (P＜0.001). Conclusions LUTS is dangerous factor for sexual dysdysfunction, and the severity of LUTS is closely related to the development of sexual dysfunction. Cardura can at once improve the sexual function and LUTS of BPH patients.
