Frequency domain parameter of heart rate variability and its circadian rhythm in type 2 diabetes with lower extremity neuropathy

VernacularTitle:2型糖尿病下肢神经病变心率变异性频域参数的昼夜节律
Author: Qiang XU ; Liming CHEN ; Chunyan SHAN
Publication Type:Journal Article
Keywords: Diabetes mellitus,type 2; Diabetic autonomic neuropathy; Heart rate variability; Circadian rhythm
From: Chinese Journal of Endocrinology and Metabolism 2011;27(2):142-144
CountryChina
Language:Chinese
Abstract: Heart rate variability(HRV)analysis and its circadian rhythm(CR)were determined in 58patients with type 2 diabetes mellitus with lower extremity neuropathy(diabetic neuropathy group), 59 patients with type 2 diabetes mellitus without lower extremity neuropathy(diabetes group), and 50 healthy controls according to 24-hour Holter recording. Frequency domain parameters of HRV were significantly decreased in both diabetes groups. Frequency domain parameter of HRV in healthy controls,and daytime/nighttime difference were statistically significant. CR of HRV was changed in diabetes group and disappeared in diabetic neuropathy group. Impaired and seriously impaired autonomic nervous function developed in type 2 diabetes mellitus without and with lower extremity neuropathy respectively.