Urinary interleukin-6 level was associated with urinary tract infection in patients with type 2 diabetes mellitus
10.3760/cma.j.issn.1000-6699.2011.03.006
- VernacularTitle:尿白细胞介素6水平与2型糖尿病合并尿路感染相关
- Author:
Yun DENG
;
Xiaobo FEN
;
Rong PENG
;
Weihong YU
;
Lijun ZOU
;
Lijuan YANG
;
Wei CHENG
;
Ruipin HE
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Urinary tract infection;
Interleukin-6
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(3):213-214
- CountryChina
- Language:Chinese
-
Abstract:
The association of urinary cytokine concentration with the incidence of urinary tract infection in patients with diabetes mellitus was explored. Urinary interleakin-6 (IL-6) level in 156 female type 2 diabetes mellitus patients was tested and followed up for 6 months. The incidence of urinary tract infection between the top quartile of baseline urinary cytokine concentration with the bottom quartile was compared. The incidence of top quartile of urinary IL-6 concentration at baseline was significantly lower than that of bottom quartile ( 13.5% vs 37.8%, P＜0.05 ). Abnormality of urinary IL-6 concentration may be involved in the mechanism leading to higher prevalence of urinary tract infection in patients with diabetes mellitus.
