The accuracy of real-time continuous monitoring system at different stages and its association with glucose excursion
10.3760/cma.j.issn.1000-6699.2011.03.009
- VernacularTitle:实时动态血糖监测系统在不同时段检测的准确性变化特征及其与血糖波动的关系
- Author:
Yingying WANG
;
Qiang LI
;
Ping YU
;
Ping GAO
;
Yanhui WU
;
Can CUI
;
Wei WANG
;
Lili CHEN
;
Hong QIAO
;
Lihong WANG
;
Ying XIANG
;
Zhong ZHANG
;
Jinchao ZHANG
- Publication Type:Journal Article
- Keywords:
Real-time continuous monitoring system;
Fasting periods;
Postprandial periods;
Accuracy;
Glucose excursion
- From:
Chinese Journal of Endocrinology and Metabolism
2011;27(3):224-228
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the accuracy of real-time continuous monitoring system (RT-CGMS) at different stages and its association with glucose excursion. Methods Totally 33 patients with type 1 diabetes or type 2diabetes were under surveillance of RT-CGMS for 5 d. Capillary glucose values were measured 7 times daily.Correlation coefficient, error grid analysis (EGA), and Bland-Altman analysis methods were used to assess the correlation, accuracy and agreement of RT-CGMS at different stages and in general level; The mean amplitude of glucose excursion (MAGE) and the frequency of glucose excursion ( FGE ) were also calculated. Results ( 1 ) The correlation coefficient of RT-CGMS with capillary glucose values at fasting, postprandial stages, and in general level were 0.94,0.92, and 0.93 respectively( P<0.01 ). (2) EGA showed that 98.82%, 98.39%, and 98.64% of the results fell in the A and B zones and 1. 18%, 1.61%, and 1.36% fell in the D zone respectively at fasting,postprandial stages, and in general level. There is no result fell in C and E zones. ( 3 ) The agreement analysis showed that RT-CGMS readings were in close agreement with capillary glucose values at fasting, postprandial periods, and in general level. (4)The MAGE at fasting, postprandial periods, and in general level were (3.57±2.66), (4.07±3.09), and (4. 02 ±3.04) mmol/L (P>0. 05), (0±0. 5), (3± 1), and( 1 ±3) d for FGE (P<0. 01 ).Conclusion RT-CGMS at fasting stage has higher accuracy than postprandial stage and general level, FGE at fasting stage is higher than postprandial stage and general level.