Bullous Scabies with Bullous Pemphigoid.
- Author:
Jin Hee KANG
1
;
Ji Hyun LEE
;
Tae Yoon KIM
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. tykimder@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Bullous pemphigoid;
Bullous scabies
- MeSH:
Blister;
Dermis;
Eosine Yellowish-(YS);
Eosinophils;
Epidermis;
Fluorescent Antibody Technique, Direct;
Fluorescent Antibody Technique, Indirect;
Humans;
Immunoglobulin G;
Lymphocytes;
Male;
Microscopy;
Middle Aged;
Mites;
Pemphigoid, Bullous*;
Sarcoptes scabiei;
Scabies*;
Skin;
Skin Tests;
Steroids;
Transcutaneous Electric Nerve Stimulation
- From:Korean Journal of Dermatology
2014;52(8):563-566
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a rare case of bullous scabies with bullous pemphigoid in a 59-year-old male patient. He presented with a 9-month history of exhibiting multiple, variable-sized, red-to-brown, pruritic cutaneous patches, and papules with tense bullae on his whole body. A direct smear of the bullous lesions was performed and was negative for scabies mites. Histopathologic findings (hematoxylin and eosin staining) revealed Sarcoptes scabiei in the stratum corneum. There were sub-epidermal blisters with massive eosinophil and lymphocyte infiltration in the epidermis and upper dermis. Direct immunofluorescence microscopy showed linear deposition of IgG at the dermo-epidermal junction. Indirect immunofluorescence microscopy of samples acquired for the salt-split skin test showed linear IgG deposition in the epidermis. Skin lesions improved after the patient was treated with an anti-scabietic and steroids.