Abrupt Onset of Palisaded Neutrophilic and Granulomatous Dermatitis in a Patient with Rheumatoid Arthritis.
- Author:
Seung Hwan CHOI
1
;
Seung Min HA
;
Dong Yeob KO
;
Ki Hoon SONG
;
Ki Ho KIM
Author Information
1. Department of Dermatology, College of Medicine, Dong-A University, Busan, Korea. khkim@dau.ac.kr
- Publication Type:Case Report
- Keywords:
Abrupt onset;
Palisaded neutrohpilic and granulomatous dermatitis;
Rheumatoid arthritis
- MeSH:
Arthritis, Rheumatoid*;
Collagen;
Dermatitis*;
Dermis;
Dust;
Elbow;
Female;
Fibrin;
Histiocytes;
Humans;
Inflammation;
Middle Aged;
Mucins;
Neutrophils*;
Vasculitis
- From:Korean Journal of Dermatology
2014;52(8):567-570
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Palisaded neutrophilic and granulomatous dermatitis (PNGD) is characterized histopathologically by the presence of granulomatous inflammation with or without leukocytoclastic vasculitis. It has been associated with multiple systemic diseases, particularly autoimmune conditions like rheumatoid arthritis and Behcet's disease. We report a 52-year-old woman with rheumatoid arthritis who presented with a single, non-tender, rapidly growing nodule on her right elbow. Histologic examination of the nodule revealed degenerated collagen, neutrophils, neutrophilic dust, fibrin, and mucin present in the centers of the palisades of histiocytes throughout the dermis. Herein, we report the abrupt onset of PNGD in a patient with rheumatoid arthritis.
