The analysis of clinical related factors of recurrence and metastasis of gastric cancer after radical gastrectomy
10.3760/cma.j.issn.0254-1432.2011.01.005
- VernacularTitle:胃癌根治术后复发转移临床相关因素分析
- Author:
Liangliang WU
;
Han LIANG
;
Xiaona WANG
;
Rupeng ZHANG
;
Yuan PAN
;
Baogui WANG
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Neoplasm recurrence,local;
Lymphatic metastasis
- From:
Chinese Journal of Digestion
2011;31(1):17-20
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the occurance and risk factors of recurrence and metastasis of gastric cancer after gastrectomy.Methods From January 2001 to December 2004, the clinic pathological data of 141 patients with recurrence and metastasis after radical gastrectomy in Tianjin Medical University Cancer Institute and Hospital were analyzed retrospectively.The possible clinic pathological factors which may affect tumor recurrence were analyzed.Results After the surgery, the 1, 2, 3 and 5-year cumulative recurrence rates were 58.2%(82/141) 、80.1%(113/141)、89.4%(126/141) 、97.9 % (138/141)respectively.The results of multivariate analysis indicated that the tumor size,invasive depth, lymph node metastasis were independent factors which affected recurrence and metastasis after radical gastrectomy (P = 0.017, 0.003, 0.000).Invasive depth, lymph node metastasis and tumor differentiation degree were independent factors which affected early recurrence and metastasis after radical gastrectomy (P=0.042, 0.000, 0.039).Conclusions The tumor size,invasive depth, lymph node metastasis are the independent risk factors to predict the recurrence and metastasis after radical gastrectomy.Most of the recurrences and metastasis is found within 2 years after radical gastrectomy.Invasive depth, lymph node metastasis and tumor differentiation degree are the independent factors to predict early recurrence after radical gastrectomy.
