Efficacy of different surgical treatment of 104 patients with hilar cholangiocarcinoma and survival analysis
10.3760/cma.j.issn.1008-6315.2011.03.026
- VernacularTitle:不同术式治疗104例肝门胆管癌疗效及生存分析
- Author:
Qiuxue ZHANG
;
Dongshan YANG
;
Zhiquan ZHANG
;
Lei ZHANG
;
Xuefeng LI
;
Xin CHEN
- Publication Type:Journal Article
- Keywords:
Bile duct tumors;
Surgery;
Prognosis
- From:
Clinical Medicine of China
2011;27(3):295-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficacy of surgical treatment in hilar cholangiocarcinoma patients. Methods One hundred and four cases underwent surgical treatment of hilar cholangiocarcinoma were retrospective enrolled in the study from 1998 to 2008, including 45 cases of radical resection, 38 cases of palliative resection, vitro bridge drainage in 21 cases, 93 cases of postoperative patients. Ninty-three patients were followed up for 5 - 67 months, the different procedures of the treatment was summerized. Results Oneyear survival rate of radical resection and palliative resection was 80. 0% ( 32/40 ) and 86. 8% ( 33/38 ),respectively. No significant difference between the two groups (P ＞0. 01 ) were found; 2-year survival rate was 67. 5% (27/40) and 39. 5% ( 15/38), with significant difference between the two groups (P ＜0. 01 ) ;3-year survival rates were 37.5% ( 15/40 ) and 13.2% ( 5/38 ), with significant difference between the two groups (P＜0. 05). Palliative resection had higher 1-year survival rate than in vitro bridge drainage(P ＜ 0.01).Conclusion Surgical treatment of hilar cholangiocarcinoma is the most effective way to prolong the survival time of radical resection, radical surgery had better efficacy than palliative surgery, and palliative surgery is superior to external drainage. In patients of severe jaundice combined with biliary drainage infection, preoperative bridge drainage would improve the safety.
