Diagnostic value of colon capsule endoscopy for active ulcerative colitis
10.3760/cma.j.issn.1007-5232.2011.04.007
- VernacularTitle:胶囊结肠镜对结肠黏膜炎症性改变的诊断价值初探
- Author:
Chenan YE
;
Yunjie GAO
;
Zhizheng GE
;
Jun DAI
;
Xiaobo LI
;
Hanbing XUE
;
Zhihua RAN
;
Yunjia ZHAO
- Publication Type:Journal Article
- Keywords:
Colon capsule endoscopy;
Ulcerative colitis;
Colonoscopy;
Diagnosis
- From:
Chinese Journal of Digestive Endoscopy
2011;28(4):196-199
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate diagnostic value of colon capsule endoscopy (CCE) for mucosal lesions of patients with active ulcerative colitis. Methods A total of 19 consecutive patients, including 12 males and 7 females, were enrolled from July 2009 to June 2010, with a mean age at 44. 16 + 14.64.Dominant symptoms were hematochezia, diarrhea and abdominal pain, consistent with the criteria of ulcerative colitis. All cases were scored into 3 grades according to severity of mucosal lesions. Using conventionalcolonoscopic findings as golden standard, the consistence of mucosal classification of CCE was calculated with kappa- and P-value. Meanwhile, related data such as the rate of completion, colonic cleanliness and adverse reactions were also collected and analyzed. Results CCE revealed that mild, moderate and severe cases were 2, 8 and 9, respectively, while the 3 types shown by conventional colonoscopy were 3, 8 and 8,respectively. Kappa-value was 0. 826 and P-value was less than 0. 001, which indicated good consistence. In addition, the completion rate of CCE and excellent/fine rate of the colonic cleanliness were 100% (19/19)and 79% ( 15/19), respectively. There were no adverse reactions recorded. Conclusion With high diag-nostic consistency to conventional colonoscopy in classification of mucosa severity, CCE precisely reveals the mucosal lesions of ulcerative colitis and becomes a potential alternative to partially replace conventional colonoscopy, especially in surveillance.
