Effects of gastric mucosa washing with povidone-iodine solution on bacteremia after endoscopic ultrasonography-guide fine needle aspiration

VernacularTitle:碘伏溶液冲洗胃黏膜对超声内镜引导下细针穿刺术后菌血症发生率的影响
Author: Na LI ; Siyu SUN
Publication Type:Journal Article
Keywords: Endosonography; Biopsy,fine-needle; Bacteremia; Cell culture techniques; Povidone-iodine solution
From: Chinese Journal of Digestive Endoscopy 2011;28(2):67-70
CountryChina
Language:Chinese
Abstract: Objective To study the occurrence of bacteremia and whether washing gastric mucosa with povidone-iodine could reduce its occurrence after endoscopic ultrasonography (EUS)-guided fine needle aspiration (FNA). Methods A total of 20 healthy adult dogs were randomly assigned into experimental group and control group, with 10 in each. The animals in experimental group underwent gastric mucosa washing with 10 ml 0. 5% povidone-iodine solution before FNA, while those in control group with 10ml normal saline. Blood samples were collected for culture before EUS, between EUS and FNA, and 5, 15 and 30 minutes after FNA. Results There were 3 cases of positive bacteremia in experimental group and l in control group,which were not significantly different ( P = 0. 582). Conclusion Pre-washing gastric mucosa with 0. 5% povidone-iodine solution cannot reduce bacterial infection after EUS-guided FNA.