Clinical analysis of fibrolamellar hepatocellular carcinoma,two cases report and a review of the literature
10.3760/cma.j.issn.1006-9801.2011.04.008
- VernacularTitle:纤维板层型肝癌二例报道及文献复习
- Author:
Liguo LIU
;
Liming WANG
;
Jianxiong WU
;
Weiqi RONG
;
Yuxin ZHONG
;
Fan WU
;
Quan XU
;
Yipeng WANG
;
Chengli MIAO
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Hepatectomy;
Diagnosis
- From:
Cancer Research and Clinic
2011;23(4):240-242
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features,imaging and pathologic findings of fibrolamellar hepatocellular carcinoma (FL-HCC).Methods Clinical data from 2 patients with FL-HCC confirmed by operation were analyzed retrospectively.Results There were 1 man and 1 woman,both of them were younger than 40 years.The man had hepatitis B,the woman did not have underlying hepatitis.The 2 patients had a normal hepatic function and α-fetoprotein level.Under dynamic contrast material-enhanced computed tomography,hepatic arterial phase CT images demonstrated heterogeneous enhancement of the tumor.Calcification was depicted in the CT images of 1 patients.Both of them underwent a successful operation.After 8 months of follow-up,1 patient had recurrence.And the other patient had no evidence of recurrence during 16 months follow-up time.Conclusion FL-HCC is a rare liver tumor that has distinct clinicopathologic features comparing with hepatocellular carcinoma.Most of FL-HCC occurs in young patients with normal level of α-fetoprotein and no history of hepatitis.Tumors may have calcification and become predominantly on hepatic arterial phase CT images.The most effective treatment for FL-HCC is surgical resection and prognosis is good.
