Progress of the relationship between vitamin D and allergy diseases
10.3760/cma.j.issn.1673-4408.2011.03.031
- VernacularTitle:维生素D与过敏性疾病相关性的研究进展
- Author:
Guanghua CHEN
- Publication Type:Journal Article
- Keywords:
Vitamin D;
Allergy disease;
T cell;
Denditic cell
- From:
International Journal of Pediatrics
2011;38(3):304-306
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of allergy diseases is increasing globally. Epidemiological surveies showed that the increased allergy prevalence rates followed the time trend of rickets prophylaxis in western countries. and vitamin D supplement increased the risk of allergy in early stage.Currently,most of investigators think that vltamin D deficiency may be one of the risk factors for allergy diseases.Laboratory investigations showed that vitamin D inhibited Th1、dendritic cell(DC)and Th2 cell proliferating,and keeped on epithelial suIfaces barrier tunction.However,no study has found generating of allergy disease is associated with vitamin D deftciency or excess.