Oxidative stress, oxidized low density lipoprotein, lipoprotein-associated phospholipase A2 and atherosclerosis
10.3760/cma.j.issn.1673-4165.2011.03.012
- VernacularTitle:氧化应激、氧化低密度脂蛋白和脂蛋白相关磷脂酶A2与动脉粥样硬化
- Author:
Jie YAN
;
Guorong LIU
;
Yuechun LI
;
Baojun WANG
- Publication Type:Journal Article
- Keywords:
Atherosclerosis;
Oxidative stress;
Reactive oxygm species;
oxidized lowdensity hpoprotein;
1-Alkyl-2-acetylglycerophosphocholine cstcrase;
Risk factors
- From:
International Journal of Cerebrovascular Diseases
2011;19(3):237-240
- CountryChina
- Language:Chinese
-
Abstract:
Oxidative stress is 811 important risk factor for premature athcrosclcrosis.Itis involved in a variety of pathophysiological processes,including mitochondrial damage,freeradical release,lipid peroxidation,phospholipase activation,and infl~niatory modiator release.A growing body of research suggests that oxidative stress,oxidized low density hpoprotein,andlipoprotein-associated phospholipase A2 Play important roles in the occurrence and developmentof athcrosclcrosis.Therefore,investigating their relationship contributes to deepen theunderstanding of athcrosclerosis and take appropriate preventive measures.
