Progress in the relationship between environmental estrogen bisphenol A and obesity
10.3760/cma.j.issn.1673-4408.2011.03.025
- VernacularTitle:环境雌激素双酚A与肥胖关系的研究进展
- Author:
Jing WANG
- Publication Type:Journal Article
- Keywords:
Bisphenol A;
Estrogen;
Obesity
- From:
International Journal of Pediatrics
2011;38(3):283-286
- CountryChina
- Language:Chinese
-
Abstract:
Bispheno|A(BPA)is an endocrine disruptor with estrgenic properties,which is a widely used industrial platicizer.When exposure to BPA for long-term,it would impact on multiple systems and organs including reproductive.developmental,neurological,endocrine function and so on,particularly in obesity.ExpoSUre to BPA during pregnancy and postnate,it can increase the sensitivity to obesity in offsprings.BPA may be contributed to obesity by enhancing triglyceride accumulation and accelerating adipocytes differentiation,affecting endocrine function of adipocytes and blood glucose and insulin metabolism.However,the dosage effect of BPA is not a simple linear rehionship.The impact of environment-related dosage on the human is worthy ot research in future.
