Progress of bone marrow-derived mesenchymal stem cells and bronchopulmonary dysplasia
10.3760/cma.j.issn.1673-4408.2011.03.007
- VernacularTitle:骨髓间充质干细胞与支气管肺发育不良的研究进展
- Author:
Min YANG
- Publication Type:Journal Article
- Keywords:
Bone marrow mesenchymal stem cells;
Hyperoxia;
Lung injury
- From:
International Journal of Pediatrics
2011;38(3):226-229
- CountryChina
- Language:Chinese
-
Abstract:
Bronchopulmonary dysplasia is a chronic lung disease of newborn.In recent vears.its incidence is increasing.Bone marrow derived mesenchymal stem cells(BMSC)have been shown to differentiate into a variety of mesenchymal cell types.It has been shown that these cells can be separated.purificated.amplificated and administered to animals and patients in clinical trials.This article focuses on the pathology.pathogenesis of the bmnchopulmonary dysplasia,and biological characteristics of BMSC,and indicates that the cells in the circulation Can engraft in the lung and offer effective protection against lung injuries.
