Comparative research on the adverse reaction of the intravenous injection of sodium thiosulfate and calcium gluconate
10.3760/cma.j.issn.1672-7088.2011.13.031
- VernacularTitle:静脉推注硫代硫酸钠与葡萄糖酸钙不良反应发生情况的比较研究
- Author:
Zhulin LI
;
Bin WU
;
Hongying WU
;
Sai YUE
;
Meiling XU
;
Xiaolan WEN
;
Yufeng GUO
- Publication Type:Journal Article
- Keywords:
Sodium thiosulfate;
Calcium gluconate;
Adverse reaction;
Intravenous injection
- From:
Chinese Journal of Practical Nursing
2011;27(13):64-66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the incidence of adverse reaction,clinical manifestation and serious degree of adverse reaction and the intravenous injection time of the two different drugs,and provide references for the safe dosage of the drugs in clinic.Methods 200 patients from June 2009 to June 2010,who visited department of dermatology because of allergic dermatitis were chosen.They were randomly divided into the sodium thiosulfate group and the calcium gluconate group according to the drugs which were injected intravenouly.And incidence of adverse reaction,clinical manifestation and serious degree of adverse reaction and the intravenous injection time were compared between two groups.Results Compared with the calcium gluconate group,the rate of the adverse reaction of the sodium thiosulfate group is lower,and the average time needed is shorter,in addition,there is no serious adverse reaction during injection.Conclusions Intravenous injection of sodium thiosulfate has the advantage of lower incidence of adverse reaction,shorter time needed,and fewer serious adverse reaction,which is worthy of wide spread.
