Research development of leukotriene receptor antagonists as treatment for children with asthma
10.3760/cma.j.issn.1673-4408.2011.03.032
- VernacularTitle:白三烯受体拮抗剂治疗儿童哮喘的研究进展
- Author:
Hong ZHANG
;
Yun GAO
;
Hongxia ZHAO
- Publication Type:Journal Article
- Keywords:
Asthma;
Leukotriene;
Leukotfiene receptor antagonists;
Montelukast
- From:
International Journal of Pediatrics
2011;38(3):307-310
- CountryChina
- Language:Chinese
-
Abstract:
Leukotriene is a crucial inflammation medium in the process of asthma,involved in the inflammation and remodeling of airway.This article summarizes the origin,synthesis and biological activity of leukotriene in asthma.and discuss the implications of leukotriene receptor antagonists(Montelukast)for asthma in children.The randomized.double-blind and muhicenter clinical trials are needed to determine the efficacy of Montelukast in infants less than 2 years old with asthma.
