Progress of human rhinovirus infection and asthma
10.3760/cma.j.issn.1673-4408.2011.03.009
- VernacularTitle:人类鼻病毒感染与哮喘研究进展
- Author:
Meiyi WANG
- Publication Type:Journal Article
- Keywords:
Rhinovirus;
Asthma;
Acute exacerbation
- From:
International Journal of Pediatrics
2011;38(3):232-235
- CountryChina
- Language:Chinese
-
Abstract:
Human rhinovirus(HRV)is a common pathogen causing respiratory tract infection.and recent studies have shown that HRV infection is not only a cause of asthma acute exacerbation.but their early infection in infants and young children also plays an important role during the formation of asthma in children.HRV causes asthma relevant symptoms mainly by the following mechanisms,infection of bronchial epitheIial cells.to promote the release of inflammatory mediators.the immune response and to cause airway remodeling.Learning more about the impact of HRV infection on asthma and related mechanisms will help US to find effective prevention and treatment methods to reduce asthma morbidity and acute excerbation.