Intra-arterial thrombolysis with stenting for acute cerebral infarction
10.3760/cma.j.issn.1673-4165.2011.04.002
- VernacularTitle:动脉溶栓辅助支架置入术治疗急性脑梗死
- Author:
Yu ZHOU
;
Jingzhou WANG
;
Lili ZHANG
;
Chuanqin FANG
;
Changyue GAO
;
Qingwu YANG
;
Jingcheng LI
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain infarction;
Thrombolytic therapy;
Stents;
Tissue plasminogen activator;
Treatment outcome
- From:
International Journal of Cerebrovascular Diseases
2011;19(4):245-249
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the efficacy of intra-arterial thrombolysis with stenting for acute cerebral infarction. Methods Using a prospective case-control design, 24 patients with acute cerebral infarction who remained angiostegnosis ( ＞ 50%) after intra-arterial thrombolysis were randomly divided into stent treatment group and drug treatment group. They were treated with stenting + drug treatment and conventional drug treatment. The rates of vascular complete revascularization and residual stenosis, and the modified Rankin scale scores at 3 months in both groups were evaluated. Results The rate of complete revascularization in the stent treatment group was significantly higher than that in the drug treatment group (54. 5% vs.0%,χ2 =6.382, P ＜0. 001), and the rate of residual stenosis was significantly lower than that in the drug treatment group ([4.5 ±5.2]% vs. [82. 5 ±10. 5]%, t =7.464, P＜0.001). The rate of favorable clinical outcome in the stent treatment group was significantly higher than that in the drug treatment group (100% vs. 76. 9%,χ2 = 14. 263, P = 0.038). Conclusion The efficacy of intra-arterial thrombolysis with stenting in the treatment of acute cerebral infarction is superior to that in the drug treatment group, and it is safer.
