Effect of the side of cerebral lesion on the outcome in patients with acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2011.03.004
- VernacularTitle:病灶侧别对急性缺血性卒中患者转归的影响
- Author:
Bo SONG
;
Yuan GAO
;
Song TAN
;
Lu ZHAO
;
Zhuo LI
;
Jiameng LU
;
Guang YANG
;
Yuming XU
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain ischemia;
Functional laterality;
Risk factors;
Prognosis
- From:
International Journal of Cerebrovascular Diseases
2011;19(3):195-198
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of the side of cerebral lesion on the outcome in patients with ischemic stroke.Methods A total of 407 consecutive anterior circulation ischemic stroke patients within 14 days after symptom onset were recruited prospectively.The basic data ofthe e,~ISes were collected,such as the National Institutes ofHealth Stroke Scale (NU-ISS)and the side ofcerebral lesion.The modified Rankin Scale(mRS)was used to evaluate the prognosis of the patients at 6 raomhs.Results Of the 407 patients recruited,230 patients (56.5%)Were left hemisphere stroke,177(43.5%)were fight hemisphere stroke.After multivariable logistic recession analysis,the age(odds ratio[OR]1.022,95% confidence interval[CI]1.001-1.043,P=0.040),the side of lesion(OR 1.999.95%CI1.179.3.389.P=0.010),the time from onset to admission(OR1.006,95%(7/1.002-1.010,P=0.007),the outcome of the anterior circulation ischcmic stroke at 6 months aftel"onset.The outcome of the right hemisphere stroke Was significantly worse than that of the left hemisphere stroke.The onset-admission time in patients with right hemisphere stroke(median 12 h,median 39.61 h)was significantly delayed compared to the patients with left hemisphere stroke(median 12 h,median 22.72 h;Z=-2.962,P=0.003).Condusions The outcome of the left hemisphere stroke at 6 months after onset is superior to the right hemisphere stroke,and it mau be associated with the delayed admission.
