Orthotopic liver transplantation for hilar cholangiocarcinoma (report of 10 cases)
10.3760/cma.j.issn.1673-4203.2011.05.007
- VernacularTitle:原位肝移植术治疗肝门胆管癌(附10例报告)
- Author:
Ming PAN
;
Guangwen ZHOU
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Cholangiocarcinoma;
Treatment
- From:
International Journal of Surgery
2011;38(5):304-307
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficacy of the orthotopie liver transplantation for hilar cholangiocarcinoma and analyse relevant factors.Methods A retrospective study was conducted in 10 cases of hilar cholangiocarcinoma treated with orthotopic liver transplantation from 2002 to 2010.Results The male:fe5 and 8 years were 70.0%and 60.4%.50.9%and 50.9%,respectively.No tumor survival rates for 1,3,5 and 8 year were 65.3%,58.7%,50.9%and 50.9%,respectively.Operative time was(306.7±38.1)min.The average blood loss was(659.4±300.6)mL.Multiple regression analysis showed that positive lymph nodes(P=0.0092)positive surgical margin(P=0.0028)and neural invasion(P=0.021)were the most important factor affecting hilar cholangiocarcinoma recurrence after liver transplantation.Conclusions Orthotopic liver transplantation for hilar cholangiocarcinoma is an effective means.Intraoperative radical resection will receive a good effect.Resection margin and lymph node-positive are the most important factors affecting long-term survival.
