Predictive value of umbilical cord blood bilirubin level for neonatal pathological jaundice
10.3760/cma.j.issn.1673-4904.2011.15.009
- VernacularTitle:脐血胆红素预测新生儿病理性黄疸的价值
- Author:
Shanxia WU
;
Siguo FENG
;
Zhengshan CHEN
;
Guirong WU
;
Guanghui FANG
- Publication Type:Journal Article
- Keywords:
Infant,newborn;
Jaundice;
Fetal blood;
Bilirubin
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(15):21-22
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the predictive value of umbilical cord blood bilirubin for pathological jaundice in healthy term newborns. Methods Two ml navel string vein blood of baby were collected after giving birth in the normal newborn, and the hemobilirubin was detected by accidentally oxidation method. After birth, the infant's bilirubin level was tested on the forehead by the transcutaneous bilirubinometer at 8:00 -9:00 every morning until discharging from hospital. The ration of pathological jaundice of newborn and its treatment were analyzed in different levels of cord blood hemobilirubin. Results Fifty-nine cases ( 22.96% ) with pathological jaundice were diagnosed in 257 newboms.The concentration of cord blood hemobilirubin in baby with pathological jaundice [(39.68 ±8.10) μmol/L] was significantly higher than that of the normal newborn [(30.05 ±5.51) μmol/L](P＜0.01). As the concentration of cord blood hemobilirubin was increased, the incidence of pathological jaundice was raised (P＜ 0.01), and the cases that needed to intervention treatment was increased(P＜ 0.01). Conclusion The detection of the level of cord blood hemobilirubin is not only very worthy to estimate the occurrence of pathological jaundice of newborn, but also offer reliable evidence for clinical early diagnosis and treatment.
