Risk factors and treatment experience of cerebral aneurysms rupture in the course of Gugliemi detachable coil embolization
10.3760/cma.j.issn.1673-4904.2011.14.012
- VernacularTitle:颅内动脉瘤在电解可脱式弹簧圈栓塞术中破裂危险因素分析及处理体会
- Author:
Zhensheng XUE
- Publication Type:Journal Article
- Keywords:
Intracranial aneurysm;
Rupture;
Risk factors;
Guglielmi detachable coil
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(14):29-31
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors and treatment experience of cerebral aneurysms rupture in the course of Gugliemi detachable coil (GDC) embolization. Methods From August 2000 to June 2010,420 patients with aneurysmal subarachnoid hemorrhage (SAH) received GDC embolization and their clinical data were retrospectively reviewed to analyse the risk factors of cerebral aneurysms rupture in the course of treatment. Results Sixteen patients had intraoperative aneurysm rupture, the incidence rate was 3.8%(16/420),including 13 cases density filling,3 cases partial filling postoperative.Univariate analysis showed:SAH episodes ≥2 times,tumor size ≤4 mm,the presence of pseudoaneurysm,Hunt-Hess grade Ⅳ - Ⅴ as well as history of hypertension were the risk factors of cerebral aneurysms rupture in the course of GDC embolization. Logistic regression analysis showed:SAH episodes ≥2 times (P = 0.0424,OR =6.798)and the presence of pseudoaneurysm (P = 0.0069, OR = 4.423) were the independent risk factors of cerebral aneurysms rupture. Conclusions Rupture of intracranial aneurysm in the course of GDC embolization is mainly related to the multiple SAH and the presence of pseudoaneurysm. It should be alert to the risk factors and take active treatment as soon as the occurrence of rupture in clinic work, for this, most patients can get a good prognosis.
