The comparison on the effect of different ventilation modes in chronic obstructive pulmonary diseases combined with respiratory failure
10.3760/cma.j.issn.1673-4904.2011.13.002
- VernacularTitle:不同通气模式在慢性阻塞性肺疾病合并呼吸衰竭方面的效果比较
- Author:
Fucheng WU
- Publication Type:Journal Article
- Keywords:
Respiration,artificial;
Pulmonary diseases,chronic obstructive;
Respiratory insufficiency
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(13):4-6
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study and compare the effect of different ventilation modes in chronic obstructive pulmonary diseases (COPD) combined with respiratory failure. Methods Fifty patients with COPD combined with respiratory failure were divided into group A and group B with 25 cases each by random digits table,and they were treated with invasive positive pressure ventilation. Then the two groups were respectively treated with synchronized intermittent mandutory ventilation (SIMV) + pressure suppert ventilation (PSV) and PSV + positive end-expiratory pressure (PEEP) after appearing the pulmonaryinfection-control- window. And the time of mechanical ventilation, length of hospital stay, reintubation rate, complication rate and serum interleukin (IL)-8,high Sensitiveity c-reactive protein (hs-CRP), IL-4 and interferon (IFN)- γ of the two groups before and after the treatment was analyzed and compared. Results The time of mechanical ventilation and length of hospital stay in group B was shorter than that in group A [(11.8 ± 2.3), (16.8 ± 3.2) d vs. (20.3 ± 2.0), (28.8 ± 4.1) d], and the reintubation rate and complication rate was lower than that in group A [8%(2/25), 8%(2/25) vs. 24%(6/25), 24%(6/25)]. The levels of serum IL-8, hs-CRP, IL-4 and IFN- 7 were lower in group B than those in group A (P ＜ 0.05). Conclusion The effect of nasal mask inhaled oxygen early given to COPD combined with respiratory failure is better, and it should be paid attention to.
