Clinical observation of transarterial infusion chemotherapeutics in treatment of advanced pancreatic carcinoma

VernacularTitle:化疗药物区域性动脉灌注介入治疗胰腺癌24例临床观察
Author: Hongfu LI
Publication Type:Journal Article
Keywords: Pancreatic neoplasms; Antineoplastic combined chemotherapy protocols; transarterial chemotherapy
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(6):761-762
CountryChina
Language:Chinese
Abstract: Objective To investigate the efficacy and toxicity of infusion of chemotherapeutics through artery to treat advanced pancreatic carcinoma. Methods 46 patients with advanced pancreatic carcinoma were divided into experiment group ( n = 24) and control group ( n = 22). The way of administration of experiment group and control group were through artery or through vein respectively. Results Objective remission rate was 45.83% (11/24) clinical benefit rate was 58.33% (14/24) .median survival time was 16 months(from6 ～23months) in infusion-through-artery group, while those in infusion-through-vein group were18. 18% (4/22) ,27. 27% (6/22) ,7 months (from 3 -18months) respectively. All had significant diferences between two groups (P ＜ 0.05). Conclusion To treat patients with advanced pancreatic carcinoma,transarterial infusion chemotherapeutics was more effective,the toxicity was endurable.