Clinical evaluation of wheezing infants with viral infections
10.3760/cma.j.issn.1008-6706.2011.06.013
- VernacularTitle:两种方法治疗婴幼儿病毒感染性疾病并发喘息的临床评价
- Author:
Rong YU
;
Zhongyong XIE
;
Kaiping WANG
- Publication Type:Journal Article
- Keywords:
Montelukas;
Glucocorticoid;
Infants and young children;
Wheezing;
Effect
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(6):749-750
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effects of montelukes in treatement of wheezing infants with viral infections. Methods 90 wheezing infants with viral infections were divided into oral Montelukas treatment( Group A) 50 cases and inhaled corticosteroid treatment (Group B) 40 cases, Group B were treated with conventional therapy plus glucocorticoids, Group A in addition to therapy with Montelukast 4mg/time at a draught quaque nocte for 10 days. The clinical effect 、improvement of symptoms 、 pulmonary function, blood gas analysis and the side effects were observed for the infants in both groups. Results The viral infections-positive with first break in 70 cases (77. 7% ) were significantly higher than that recurrent break in 20 cases (22.2% ) (x2 =6. 65, P ＜ 0.01) ; The scores of PaO2 after treatment were significantly higher than before treatment in two groups( t = 2. 542,2.533,all P ＜ 0. 05 ) ; A total effective rate was 88. 0% in group A which was significantly higher than that 72. 5% in group B( x2 = 3. 751 ,P ＜ 0.05) ;The adverse reactions incidence 4. 0% (2/50) in group A was significantly lower than the B group 10. 0% (4/40) in group B(x2 =3.857,P＜0.05). Conclusion Montelukast had definitely effect for infant wheezing with virus infection, and had less side effects.
