Studs on effect of nebulised budesonide in treatment of neonatal laryneal edema caused by mechanical ventilation
10.3760/cma.j.issn.1008-6706.2011.10.014
- VernacularTitle:布地奈德雾化吸入治疗新生儿气管插管后喉头水肿的临床观察
- Author:
Ying LIU
;
Qiusheng GE
;
Yuxin ZHOU
- Publication Type:Journal Article
- Keywords:
Budesonide;
Nebulised;
Ventilators,mechanical;
Laryneal edema;
Infant,newborn
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(10):1325-1326
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinicd effect of using nebulised budesonide to treat neonatal laryneal edema caused by mechanical ventilation.Methods 43 newborns with mechanical ventilation were included in this study and divided into two groups:The Observational group(23 newborns)were treated with nebulised budesonide right before excubation once and three times after that,and the control group(20 newborns)were treated with dexamethasone once right before excubation and nebulised adrenine after that for three times.Comparisons were made between two groups about dismissing time of wheeze or hoarseness,tachypnea,PaO2 and PaCO2.Results Observational group:dismissing time of wheeze or hoarseness was(10.26±4.01)hours,dismissing time of tachypnea was(1.63±0.55)days,which was shorter than that of control group[(14.20±5.58)hours/(2.05±0.58)days],P＜0.05).PaO2 and PaCO2 of two groups had no statistical difference(P＞0.05).Conclusion Nebulised budesonide was effective in treatment neonatal laryneal edema caused by mechanical ventilation,using.
