Comparison of the curative effect of two treatment methods on patients with chronic nephritis
10.3760/cma.j.issn.1008-6706.2011.10.008
- VernacularTitle:中西药联合治疗慢性肾炎疗效观察
- Author:
Naihuo GUO
;
Jianyuan CHU
;
Chunfeng RAN
- Publication Type:Journal Article
- Keywords:
Glomernlonephritis,chronic;
TCM-WM therapy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(10):1312-1314
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the curative effect and adverse reactions in patients with chronic nephritis by two treatment methods.Methods 1 00 cases with chronic nephritis were randomly divided into alone western medicine group(control group)50 cases and traditional Chinese combination western medicine group(treatment group)50cases,The index of efficacy,urinary protein of 24h,serum albumin(Alb),serum creatinine(Scr),blood urea nitrogen (BUN)were observed.Results The total effective rate 78.0%in treatment group was significantly higher than 52.0%in control group(x2=3.841,P<0.05);Three sub-types showed no significant efficacy difference(x2=1.841,P>0.05);The contents of urine protein,BUN,Scr levels after treatment were lower than before treatment in two groups(t=2.231,2.245,2.311,all P<0.05).The content of Alb after treatment was higher than before treatment(t=2.241,P<0.05);The contents of urinary protein,BUN,Scr,Alb after treatment were significantly different in two groups(t=2.241,2.285,2.301,2.295,all P<0.05);The adverse reactions in 2 cases(2.4%)in treatment group were significantly lower than 8 patients(16.0%)in control group(x2=6.941,P<0.01).Conclusion Traditional Chinese and western medicine could delay progression and obtain better clinical results in patients with chronic nephritis.