Impacts of the Decoction of Fortifying the Spleen and Supplementing Qi on the cellular immunity of chronic Hepatitis B virus carriers
10.3760/cma.j.issn.1008-6706.2011.10.003
- VernacularTitle:健脾益气方对慢性乙型肝炎病毒携带者T细胞免疫功能的影响
- Author:
Hong LIU
;
Bin WEN
;
Qikai WU
;
Xin DENG
;
Min WANG
;
Guoliang ZHANG
;
Xiaoliang LI
;
Guang NIE
- Publication Type:Journal Article
- Keywords:
Hepatitis B,chronic;
Decoction of Fortifying the Spleen and Supplementing Qi/Therapeutic Use;
T-Lymphocyte subsets
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(10):1302-1304
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the impacts of the method of fortifying the spleen and supplementing Qi on the cellular immunity of chronic hepatitis B virus(HBV)carriers.Methods Asymptomatic HBV carriers group(ASC group,n=60)with HBV DNA positive were randomly divided into Fortifying the Spleen and Supplementing Qi decoction group(A group,n=30)and conventional treatment group(B group,n=30),the peripheral blood T lymphocyte subsets were detected with flow cytometey and compared with those of the healthy people(The normal control group,n=18).All the patients were treated,and 24 weeks after treatment the indexes were measured again.Results As compared with those of normal controls,the numbers of CD4+ T cells and CD8+ T cells were decreased significantly in HBV carriers(P＜0.01);There was a statistical significance between the values before and complete the treatment with the decoction of fortifying the spleen and supplementing Qi(P＜0.05 or P＜0.01),and compared with conventional treatment group,there Was a statistical significance(P＜0.05).Conclusion T-cell subset function was disturbed in the HBV carriers.The method of fortifying the spleen and supplementing Qi could improve the cellular immunity of carriers with chronic hepatitis B.
