Valne of BNP and NT-Pro BNT testing in diagwsis of heart failure

VernacularTitle:脑钠肽和NT-Pro BNP检测在心力衰竭诊断中的意义
Author: Aihua LIU ; Xufang WANG ; Guiyun HAN
Publication Type:Journal Article
Keywords: B-type natriuretic paptid (BNP); NT-Pro BNP; Chronic heart failure (CHF)
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(8):1038-1040
CountryChina
Language:Chinese
Abstract: Objective To evaluate the clinical significance of the changes of plasma B-type natriuretic paprid and NT-pro BNP levels in patients with chronic heart failure(CHF).Methods 120 consecutive patients hospitalized for CHF were retrospectively studied.NT-pro BNP and LVEDD,LVESD,LVEF were measured and compared in 120 patients and 50 normal control subjects before medical treatment and on discharge.Results The plasma NT-pro BNP levels in patients with CHF were significantly higher than controls( P <0.05).The plasma NT-pro BNP levels in patients with cardiac function NYHA Ⅰ were significantly higher than controls( P < 0.05).As the cardiac function deteriorated from NYNA Ⅰ to NYNA Ⅳ,the NT-pro BNP levels increased consecutively with significant differences from each other ( P < 0.05).The plasma NT-pro BNP levels was low when CHF was cured ( P < 0.05 ).Conclusion Determination of plasma NT-pro BNP levels in patients with CHF were helpful to study the severity and prognosis of disease.