A Comparison of Curative Effect of Cinepazide Maleate and Nimodipine in Patients with Hypertensive Cerebral Hemorrhage after Microtraumatic Craniopuncture
10.3760/cma.j.issn.1008-6706.2011.07.025
- VernacularTitle:马来酸桂哌奇特与尼莫地平治疗高血压性脑出血术后疗效比较
- Author:
Xiao HAO
;
Xueliang LI
;
Liqiang YUE
;
Jiamin GAO
- Publication Type:Journal Article
- Keywords:
Cinepazide maleate;
Nimodipine;
Hypertensive cerebral hemorrhage;
microtraumatic craniopuncture;
curative effect
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(7):916-917
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of cinepazide maleate and nimodipine in improving the neurological function in patients with hypertensive cerebral hemorrhage after microtraumatic craniopuncture.Methods Seventy-eight patients with hypertensive cerebral hemorrhage were randomly divided into 2 groups,cinepazide maleate group (39 patients)and nimodipine group(39 patients).After 3 days operated with the microtraumatic craniopuncture,cinepazide maleate group used the amount 160mg cinepazide maleate mixed with sodium chloride injection(500ml,concentration 0.9%),and the nimodipine group uesd nimodipine(4mg)mixed with the same injection.Both the patients of the 2 groups were given intravenous drip once a day,then after continuous 14 days,the general information and the improvement of nerve were observeed.Results The total improvement rate and the improvement rate of nervous symptom was 87.2%and 61.5%respectively,in comparison,the nimodipine group was 64.1%and 39.9%.Conclusion Cinepazide maleate was better than nimodipine in improving chnical symptoms and the neurological deficit of the patients with hypertensive cerebral hemorrhage after microtraumatic craniopuncture.
