Clinical significance of the joint detection of platelet parameters and coagulation function markers in hepatitis patients
10.3760/cma.j.issn.1008-6706.2011.12.032
- VernacularTitle:病毒性肝炎患者血小板和凝血功能指标联合检测的临床意义
- Author:
Huichun CHEN
;
Yuanhong XU
- Publication Type:Journal Article
- Keywords:
Virus hepatitis;
Platelet parameters;
Coagulation function
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(12):1649-1650
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of the joint detection of platelet parameters and coagulation function markers in hepatitis patients.Methods 310 patients with viral hepatitis were divided into 4 groups:acute hepatitis group,chronic hepatitis group,serious hepatitis group and hepatocirrhosis group.The control group was the 80 healthy examination eligible people.Each group were detected platelet parameters ( PLT), mean platelet volume( MPV),.platelet distribution width( PDW),platelet large cell ratio( P-LCR), prothrombin time( PT) ,activated partial thromboplasin time (APTT ) , thrombin time ( TT) and factorl ( Fbg).Results The levels of PLT,MPV and Fbg were obviously reduced in chronic hepatitis,serious condition chronic hepatitis patients and hepatocirrhosis had significant difference compared with those in the control group (all P < 0.01).Moreover, the levels of PDW,P-LCR,PT,APTT and TT were obviously increased in the four groups compared with the control group(all P <0.05 ).Conclusion The joint detection of platelet parameters and coagulation function markers could help to observe the degree of progression of virus hepatitis,and had important clinical significance for the treatment and prognosis.
