Analysis of the efficacy of compound desogestrel combined with metformin in treatment of adolescents with polycystic ovary syndrome

VernacularTitle:复方去氧孕烯联合二甲双胍治疗青春期多囊卵巢综合征疗效分析
Author: Feilan XUAN
Publication Type:Journal Article
Keywords: Polycystic ovary syndrome; Desogestrel; Metformin
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(12):1621-1622
CountryChina
Language:Chinese
Abstract: Objective To investigate the treatment of adolescent marvelon Metformin's clinical efficacy in patients with polycystic ovary syndrome.Methods 120 cases of adolescents with polycystic ovary syndrome were randomly divided into two groups,A group of 60 patients with single-agent oral therapy Marvelon, B group of 60 patients with Marvelon oral metformin therapy ,medication time was 3 courses; The levels of fasting insulin, fasting glucose, serum sex hormone levels were compared before and after treatment.Results The hormone levels in the two groups had significant difference before and after treatment (P <0.01) ;Two groups did not change in fasting blood glucose before and after treatment,no significant difference between the two groups(P >0.05) ;The insulin levels in two groups before and after treatment,was significantly different(P <0.05).Conclusion Metformin Marvelon adolescent polycystic ovary syndrome treatment can effectively reduce the T,LH,LH/FSH,insulin resistance,clinical results were satisfactory and better than single drug therapy Marvelon.