Clinical observation of cefoperazone sodium and sulbactam sodium in treatment of 105 patients with community acquired pneumonia

VernacularTitle:头孢哌酮-舒巴坦钠治疗社区获得性肺炎105例临床观察
Author: Xianghui LI
Publication Type:Journal Article
Keywords: Cefoperazone sodium and sulbactam sodium; Community acquired pneumonia; Clinical study
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(12):1612-1613
CountryChina
Language:Chinese
Abstract: Objective To study the efficacy and safety of cefoperazone sodium and sulbactam sodium in treatment of patients with community acquired pneumonia.Methods 210 patients with community acquired pneumonia were randomly divided into two groups; 105 cases in treatment group (the patients were treated with cefoperazone sodium and sulbactam sodium), 105 cases in control group(the patients were treated with cefazolin).Both groups were treated for 7 days efficacy and safety of both groups were evaluated.Results The total effective rate was 90.48% in the treatment group and 80.00% in the control group,there were significant differences between the two groups in treatment effect rate (P <0.05).There are 3 and 2 cases in the control group and treatment group respectively has adverse effect,and there were no significant differences between the two groups' adverse effect(P>0.05).Conclusion Cefoperazone sodium and sulbactam sodium in treatment of community acquired pneumonia could obviously improve therapeutic efficacy,shorten the disease's develop course,and had a good clinical prospect.