Clinical observation on capecitabine therapy for elderly patients with malignant tumor

VernacularTitle:卡培他滨治疗老年人恶性肿瘤28例临床观察
Author: Weiping ZHANG ; Jue WANG ; Ran RAN ; Kai XU
Publication Type:Journal Article
Keywords: Neoplasms; Capecitabine; Aged
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(11):1490-1491
CountryChina
Language:Chinese
Abstract: Objective To research the therapeutic effect and toxicity of capecitabine in elderly malignant tumor patients.Methods The data of 28 elderly malignant tumor patients were retrospectively analyzed,and RECIST standard was used to evaluate therapeutic effect as CR、PR、SD and PD.In the same time,the toxicity of capecitabine was observed.Results 28 elderly malignant tumor patients who have been treated by capecitabine were completed 2cycles therapy.The effective percentage ofthese patients Was 60.7%(CR 0 pemon,PR 11 persons,SD 6 persons,PD 11 persons).The toxicity and side effect was controlled.Incidence of vomit Was 39.3%(11 persons),marrow inhibition was 25%(7 persons),angular stomatitis was 35.7%(10 persons),and hand-foot syndrome Was 21.4%(6 persons).Conclusion The therapeutic effect of capecitabine in elderly malignant tumor patients Was favourable,and the tolerance Was well.