Relations between BNP and cTnI levels detected by electrochemiluminescence immunoassay and cardiac function in patients with heart failure
10.3760/cma.j.issn.1008-6706.2011.11.013
- VernacularTitle:充血性心力衰竭患者血清脑钠肽和肌钙蛋白水平检测及意义
- Author:
Jing ZHANG
;
Hongyan ZHOU
;
Baokai ZHANG
- Publication Type:Journal Article
- Keywords:
Heart failure,congestive;
Natriuretic peptide,brain;
Cardiac troponin Ⅰ;
Heart function
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(11):1466-1467
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relations between BNP and cTnI leveh in patients with CHF and cardiac function.Methods 75 patients with CHF were selected as observation group and another 30 healthy people were selected as control group.BNP and cTnI levels were detected by electrochemiluminescence immunoassay and the data were analyzed.Results BNP and cTnI of observation group were significantly higher than control group,the difference was statistically significant(t=3.897,4.127,all P＜0.05);comparison of BNP and cTnI levels in different classification of cardiac function of observation group had significant difference(F=4.765,5.876,allP＜0.05);Linear corrlation analysis showed that:BNP and cTnI both positively correlated to classification of cardiac function(r=0.853,0.647,all P＜0.05),BNP and cTnI increased significantly with the increase of cardiac function classification.Conclusion BNP and cTnI increased significantly in patients with CHF and closely related with cardiac function.they were ideal index to evaluate the CHF severity and had a good clinical value to judge the status and function of heart in patients with CHF.
