The clinical value of growth hormone for the patients who were failed in previous IVE-ET

VernacularTitle:生长激素在体外受精失败患者中的应用价值
Author: Dongmei LI ; Ping LI
Publication Type:Journal Article
Keywords: IVF-ET Growth; Hormone
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(8):1028-1029
CountryChina
Language:Chinese
Abstract: Objective To study the application value of growth hormone in the renewal cycle for those patients who were failed in the first IVE-ET treatment.Methods 68 patients who were failed in the previous IVE-ET treatment were divided into two groups and were given long term down-regulating protocol in the first cycle and current cycle.The study group consisted of cases with using GH (4U/d)from the day of down-regulating till the day before embryo transfer and control group consisted of those without using GH.Results The rate of pregnancy of study group and control group was 26.77% and 0, while the rate of quality embryos was 46.26% and 33.58%, respectively.There was significant difference between the two groups( X2 = 3.97,4.86, P < 0.05 ), while there was no significant effect on the rate of fertilization and cleavage, the number of M Ⅱ oocytes retrieved( all P > 0.05 ).Conclusion In the second cycle,growth hormone could improve the clinical pregnancy rate and the rate of quality embryos for those patients who were failed in the first IVE-ET treatment.