Comparison of final adult height in boys with idiopathic short stature accepted growth hormone treatment or not

VernacularTitle:男童特发性矮小接受和不接受生长激素治疗最终身高的比较
Author: Yifeng NI ; Lifeng ZHOU ; Benfang YU ; Shujing TANG
Publication Type:Journal Article
Keywords: Growth hormone; Idiopathic short atature; Final adult height
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(8):1019-1021
CountryChina
Language:Chinese
Abstract: Objective In order to understand whether recombinant human growth hormone(r-hGH) can improve the idiopathic short stature(ISS) boys' final adult height(FAH).Methods We measured 16 cases diagnosed as ISS boys FAH, divided into 2 groups, of which 9 cases were not given r-hGH treatment, treatment group ,7 patients received r-hGH treatment, a dose of 0.1 ～ 0.13 U· kg-1·d-1, before going to sleep subcutaneous injection, duration of treatment was 6 ～ 20 months ( 11.9 ± 5.2 months).Results The treatment group compared with the average FAH FAH observation group had significantly improved the average(t =2.219,P<0.05).Conclusion r-hGH can improve the ISS boys FAH, but early treatment, the longer the course the more obvious effects.