Clinical value of procalcitonin in diagnosis of severe acute pancreatitis complicated with infection

VernacularTitle:降钙素原检测对重症急性胰腺炎并发感染的诊断价值
Author: Li YU
Publication Type:Journal Article
Keywords: Calcitonin gene-related peptide; Pancreatitis; Diagnosis,differential
From: Chinese Journal of Primary Medicine and Pharmacy 2011;18(11):1464-1465
CountryChina
Language:Chinese
Abstract: Objective To investigate the value of serum procalcitonin(PCT)level in diagnosis of severe acute pancreatitis(SAP)complicated with infection.Methods 65 cases of SAP who were treated as research subjects and divided into infection group with 47 cases and non-infected group with 1 8 cases according to whether complicated with infection or not.The serum PCT,C-reactive protein(CRP),white blood cell count(WBC),temperature(T)and acute physiology and chronic health standards score(APACHE-Ⅱ)of the two groups were compared and analyzed.Results The serum PCT level of SAP co-infection group was(4.58±1.20)μg/L which was significandy higher than non-infected group,the difference between groups was statistically significant(P＜0.05);but the CRP,WBC,T and APACHEⅡscore compared with non-infected group had no significant difference(P＞0.05).Conchrsion The significant increase of serum PCT level in patients with SAP maybe relate to whether complicated with infection or not.and it was a better diagnosis and observation index for SAP complicated with infection and had important clinical significance.