Contrast-enhanced ultrasound findings of chromophobic cell renal carcinoma

VernacularTitle:肾嫌色细胞癌的超声造影表现
Author: Li LEI ; Chunxiao YAO ; Bin YANG ; Ninghua FU ; Shuping WEI ; Ping LIU
Publication Type:Journal Article
Keywords: Ultrasonography; Contrast-enhanced ultrasound; Carcinoma,renal cell; Chromophobic renal cell carcinoma
From: Chinese Journal of Urology 2011;32(4):258-261
CountryChina
Language:Chinese
Abstract: Objective To discuss the imaging characteristics of chromophobic cell renal carcinoma (CCRC) and study the features on the contrast-enhanced ultrasound (CEUS). Methods The CEUS features of CCRC in 28 cases identified by pathology were reviewed. The blood supply and enhancement characteristic were observed and analyzed on time intensity curve parameters. Results The 28 cases of CCRC showed poor blood supply in contrast with the renal cortex. The CCRC presented with heterogeneity enhancement, part of the tumor took on a high wash-in and wash-out, and enhanced less intense than the surrounding renal cortex. The actinomorphous strong echo of the tumors might be revealed with CEUS in 15 cases (54%). The time intensity curve analysis demonstrated that the CCRCs' difference of peak intensity and area under the curve were lower than the renal cortex (P＜0.05), but arrival time, time-to-peak and slope of ascending curve were higher than the renal medulla (P＜0.05). Conclusion The actinomorphous enhancement and poor blood supply in the tumor of CEUS could provide diagnostic evidence for CRCC.