Factors for the recurrence after endoscopic resection of early gastric cancer
10.3760/cma.j.issn.0578-1426.2011.05.003
- VernacularTitle:早期胃癌内镜下切除术后复发的相关因素分析
- Author:
Min ZHU
;
Mingyang LI
;
Benyan WU
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms,early;
Recurrence;
Endoscopic resection
- From:
Chinese Journal of Internal Medicine
2011;50(5):366-369
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related factors of recurrence of early gastric cancer (EGC) after endoscopic resection. Methods Clinicopathologic data of 169 patients with EGC who underwent endoscopic resection and periodically followed up by the Chinese PLA General hospital were analyzed retrospectively. Results During a follow-up of 13-57 months (median time 24. 5 months), 12patients had gastric cancer again and the recurrence rate was 7. 1% (12/169). The recurrence time varied from 3 to 36 (28 ± 23)months and the median time was 18 months. The recurrence rates of 0.5 year, 1st year, 2nd year and 3rd year were 1.18% (2/169), 3.55% (6/169), 9.91% (11/111) and 12.24%(12/98), respectively. Eleven patients had gastric cancer again within 2 years after resection.Undifferentiated histology (including poorly differentiated carcinoma and signet ring cell carcinoma),submucosal infiltration and lymphovascular invasion of the primary lesion of EGC were related to thepostsurgical recurrence ( all P ＜ 0. 05). Conclusion Most recurrence of EGC occurred within 2 years afterendoscopic resecton and is related with undifferentiated histology, submucosal infiltration andlymphovascular invasion. It is important for these patients to receive endoscopy follow up.
