Serum uric acid level is a risk factor for the progress of diabetic nephropathy
10.3760/cma.j.issn.1671-7368.2011.06.023
- VernacularTitle:血尿酸对早期糖尿病肾病预后影响的分析
- Author:
Yunqiu QI
;
Guijun QIN
;
Zhangsuo LIU
;
Chunyan WANG
- Publication Type:Journal Article
- Keywords:
Uric acid;
Prognosis
- From:
Chinese Journal of General Practitioners
2011;10(6):433-434
- CountryChina
- Language:Chinese
-
Abstract:
Total 306 patients with early stage diabetes were enrolled in the study, after follow-up for 67 ± 8 months, the data of 288 cases were analyzed with survival analysis method. At the end of study 64 out 288 patients had high serum uric acid and the remaining 224 had normal uric acid levels. The prevalence of dominant proteinuria and reduced GFR were significantly higher in patients with high serum uric acid than those with normal serum uric acid (47. 36% vs 30. 29% and 66. 14% vs 37.72%, respectively, both P <0. 05). The results suggest that high level of serum uric acid is a risk factor for the progress of diabetic nephropathy.
