A randomized controlled trial of efficacy and safety of PES14LF polyethersulfone dialyzer on hemodialysis patients
10.3760/cma.j.issn.1001-7097.2011.04.006
- VernacularTitle:国产PES14LF聚醚砜透析器对血液透析患者疗效和安全性的临床随机对照试验
- Author:
Weiming ZHANG
;
Gengru JIANG
;
Jiaqi QIAN
;
Bingshun WANG
;
Chun ZHU
;
Yongmei WANG
;
Haidong HUANG
;
Yucheng YAN
;
Zhaohui NI
- Publication Type:Journal Article
- Keywords:
Hemodialysis;
Treatment outcome;
Equipment safety;
Polyethersulfone dialyzer;
Polyesulfone dialyzer
- From:
Chinese Journal of Nephrology
2011;27(4):243-246
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of PES14LF polyethersulfone highflux dialyzer on maintenance hemodialysis(MHD)patients. Methods A total of 72 MHD patients from two hospitals in Shanghai were enrolled in a randomized parallel controlled study.Conventional hemodialysis was performed for 4 h with PES14LF dialyzer in trial group and with German F6 dialyzer in control group.For each patient the study lasted one week.The clearances of urea,creatinine and phosphate were calculated.Adverse event and adverse reaction were recorded.Results There were no significant difierences of urea and creatinine clearance and reduction ratio between trial and control group.The phosphate clearance in trial group was significantly higher than that in control group[(144.57±27.83)ml/min vs(117.15±22.77)ml/min,P＜0.051.There was no significant difference of phosphate reduction ratio between trial and control group.The efficiency of urea clearance and urea reduction ratio achieved clinic effective target in two groups and no significant differences in above indexes between two groups were found. Conclusion PES14LF dialyzer is effective and safe for clinical application.
