Related factors of prevention in diabetic retinopathy
10.3760/cma.j.issn.1005-1015.2011.03.003
- VernacularTitle:糖尿病患者血糖控制相关因素与糖尿病视网膜病变发生的关系
- Author:
Li HU
;
Donghao LI
;
Hui CHEN
- Publication Type:Journal Article
- Keywords:
Diabetic retinopathy/diagnosis;
Diabetic retinopathy/prevention & control;
Risk factors;
Diabetes mellitus,type 2/complications
- From:
Chinese Journal of Ocular Fundus Diseases
2011;27(3):210-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the related risk factors for diabetic retinopathy(DR)in type 2diabetes.Methods The clinical data of 412 type 2 diabetes patients,diagnosed between 2003 and 2010,were analyzed retrospectively.The diagnosis of DR and proliferative diabetic retinopathy(PDR)was confirmed by ophthalmoloseopy and fundus fluorescein angiography.Glycated hemoglobin Alc,glucose,insulin,and C-peptide of fasting plasma,and 1,2 and 3 hours postprandial plasma were measured.According to the above-mentioned data,get the fluctuation of glucose,insulin and C-peptide of 1,2 and 3hour postprandial plasma.Results The morbidity of DR and PDR increased following the longer disease duration.Age,diabetic duration,body mass index(BMI),hypertension grade,HbAlC,fasting plasma insulin and C-peptide,2 and 3 hours postprandial plasma glucose,1 and 2 hours postprandial plasma insulin,1,2 and 3 hour postprandial plasma C-peptide,1,2 and 3 hours postprandial plasma glucose,insulin and C-peptide fluctuation are different statistically among non-DR group,non-PDR group and PDR group(P＜0.05).3 hours postprandial plasma glucose and fasting plasma insulin were risk factors of DR (P＜0.05).Conclusions Postprandial plasma glucose and fasting plasma insulin were risk factors of DR.Nevertheless,postprandial insulin,fasting and postprandial C-peptide,postprandial plasma glucose,insulin and C-peptide fluctuation were useful for DR diagnosis.
