Risk factors for occult nodal metastasis in patients with stage ⅠA peripheral non-small cell lung cancer
10.3760/cma.j.issn.1001-4497.2011.04.010
- VernacularTitle:临床ⅠA期周围型非小细胞肺癌纵隔淋巴结转移危险因素
- Author:
Luming JIN
;
Guanchao JIANG
;
Yun LI
;
Hui ZHAO
;
Jianfeng LI
;
Jun LIU
;
Jun WANG
- Publication Type:Journal Article
- Keywords:
Cancer,non-small cell lung;
Lymph nodes;
Neoplasm metastasis;
Risk factors
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2011;27(4):212-214
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the risk factors of mediastinal lymph node metastasis in patients with ≤3 cm peripheral non-small cell lung cancer.MethodsFrom January 2000 to December 2010,a total of 281 patients with NSCLC[152 men and 129 women,aged ( 60.31±12.13) years;≤ 3 cm in diameter]underwent lobectomy or partial resection with systematic mediastinal lymphadenectomy in hospital .Clinical data included age,gender,symptoms,history and quantity of smoking history,history of tumor,family history of tumor,site,diameter,calcification,speculation,border,lobulation,traction of pleural,vascular convergence sign,cavity were collected compaired and analyzed.Single and multi-variate analysis was performed to determine the independent risk of occult N2 nodal involvement.ResultsLogistic regression analysis show seven clinical characteristics (fleshless( OR:22.262),history of tumor(OR:5.485),diameter( 0R:3.788),density( OR;5.850),traction of pleural (OR:1.371),border ( OR:8.259) and cavity (OR:7.124) were risk factors.ConclusionFleshless,history of tumor,diameter,density,traction of pleural and the border and cavity were independent predictors of malignancy in patients with ≤3 cm peripheral non-small cell lung cancer.
