Intracoronary Doppler Flow Reserve Versus Dipyridamole Emission Computed Tomographic 201T1 or 99mTc-Sestamibi Myocardial Imaging
- VernacularTitle:冠脉内多普勒血流储备与核素心肌显像潘生丁试验的对比研究
- Author:
Yuehua WANG
;
Mengwu WENG
;
Hong YE
;
Zhixiang YANG
;
Guilan WU
- Publication Type:Journal Article
- Keywords:
intracoronary Doppler flowire;
dipyridamole emission computed tomographic 201T1/99m Tc-sestamibi myocardial imaging;
coronary flow reserve
- From:
Fudan University Journal of Medical Sciences
2000;27(3):215-217
- CountryChina
- Language:Chinese
-
Abstract:
PurposeTo compare measures of coronary flow reserve by an intracoronary Doppler guide wire with results of dipyridamole emission computed tomographic 201T1/ 99m Tc-sestamibi myocardial imaging(SPECT).MethodsThe coronary blood flow velocity were measured by Cardiometrics Flomap Ⅱ and 0. 014 or 0. 018 inches Doppler flowire in 27 patients (55 arteries) with coronary angiography. 8 patients (19 arteries )without underlying diseases of coronary microvascular lesions were studied as the normal control. The proximal and distal average peak velocity (APV), diastolic/systolic velocity ratio (DSVR), CFR and proximal/distal velocity ratio (P/DVR) were measured. The results were compared with that of SPECT before angiography. ResultsAccording to the CFR measured by Doppler fiowire, the arteries were divided into two groups:Group A, consisted of 33 arteries with CFR > 2.0. Group B consistedof 22 arteries with CFR≤2.0. CFR of group A was significantly higher than that of group B (P< 10 - 7). Among 22 arteries with abnormal CFR, SPECT could detect 16. Among 33 arteries with normal CFR, all arteries except 2 showed normal SPECT. With intracoronary Doppler flowire as reference, the sensitivity and specificity of dipyridamole SPECT were 72.73 % and 93.94 %. With results of dipyridamole SPECT as reference, the sensitivity and specificity of intracoronary Doppler CFR were 88.89% and 83.78%. Their conformability rate was 85.45%.Conclusions In evaluating coronary reserve function, results of dipyridamole SPECT was rather conformable to measures of intracoronary Doppler CFR, but they cannot be replaced each other.
