EFFECT OF SCHISTOSOMA JAPONICUM INFECTION ON SERUM TESTOSTERONE LEVELS IN MICE
- VernacularTitle:日本血吸虫感染对小鼠雄性激素水平的影响
- Author:
Hongbin HE
;
Ohta NOBUO
;
Kawaguchi HITOSHI
- Publication Type:Journal Article
- Keywords:
Schistosoma/aponicum;
testosterone;
mouse;
radioimmunoassay
- From:
Chinese Journal of Parasitology and Parasitic Diseases
2000;18(3):173-175
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To determine the effect of Schistosoma japonicum infection on the testoterone level in the sera from male C57BL/6 mice. [Methods] Radioimmunoassay was used to examine testosterone levels in sera of 9 male mice experimentally infected with Schistosoma japonicum. [Results] The serum testosterone levels reduced significantly in all experimentally infected animals 45 days after infection, as compared with the uninfected controls. [Conclusion] Infection with Schistosoma japonicum decreases testosterone levels in the mouse host.
