Hemodynamic Assessment of Ischemic Stroke with Near-Infrared Spectroscopy
- VernacularTitle:用近红外光谱术评价缺血性脑梗塞的血流动力学变化
- Author:
Weiguo CHEN
;
Pengcheng LI
;
Qingming LUO
;
Shaoqun ZENG
;
Bo HU
- Publication Type:Journal Article
- Keywords:
near-infrared spectroscopy;
cerebral blood flow;
cerebral infarction;
real time;
prediction
- From:Space Medicine & Medical Engineering
2000;13(2):84-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To validate near-infrared cerebral topography (NCT) as a practical toolin tracing the regional hemodynamic changes during normal ischemic stroke model of rat. Method Middle cerebral artery occlusion (MCAO) and photosensitizer induced intracranial infarction model of rat were established. The geometric shape and infarction area were measured by NCT, functional magnetic resonance imaging (fMRI), and TTC stained anatomical imaging techniques. Result In photosensitizer induced infarction model, the correlation between anatomical infarct area and NCT image area for infarct focus were r= 0.897 for 24 h group (P<0.05) and r=0.906 for 2 months group (P<0.01),respectively. The correlation between anatomical infarction area and NCT image area for infarct focus were r=0.820 for normothermia group (P<0.05) and r= 0.851 for hypothermia group (P<0.05), respectively. The correlation between fMRI and NCT image area for infarction focus were r= 0.874 for normothermia group (P<0.05) and r= 0.782 for hypothermia group (P<0.05),respectively. Conclusion Measurement with NCT for infarction focus matched well with fMRI and anatomic sample in rats. NCT technique might be a practical tool for short-term prediction of stroke and the rehabilitation after stroke in real time.
