Clinical and immunological studies on transplantation of total lamellar cornea with circular lamellar sclera on treating serious chemical burn of eye
- VernacularTitle:环行板层巩膜瓣联合全板层角膜移植术治疗严重眼部化学伤临床及免疫学探讨
- Author:
Guijun WU
;
Wei DING
;
Fangyao YANG
- Publication Type:Journal Article
- Keywords:
lamellar corneal;
corneal transplatation;
ocular chemical burn;
immunity
- From:
Recent Advances in Ophthalmology
2000;20(6):397-399
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical results of total lamellar cornea with circular lamellar sclera transplantation to treat serious chemical burn of eye and study its immunological mechanisms.Methods The patients(55 cases, 55 eyes) with corneal tansplantation were retrospectively analyzed. GroupⅠ(42 cases) was the patients with serious chemical burn of eye transplantation of total lamellar cornea with circular lamellar sclera, group Ⅱ(13 cases) was the patients transplantation of total cornea corresponding period of the groupⅠ. The time of tear-film break-up their rate of rejection and the time of occurrence of corneal neovascularization were compared.Results The time of occurrence of corneal neovascularization and rejection of group Ⅰ were later than groupⅡ.Conclusion Total lamellar cornea with circular lamellar sclera transplantation is an important method for treating serious chemical burn of eye, its immunological mechanisms is complex. It's important to increase the result of operation keeping high standard in quality of tear-film and using high effective immunosuppressive drug after operation.
