Study on bone metobolism change in thirty hyperthyroidism patients
- VernacularTitle:30例甲状腺功能亢进患者骨代谢变化的研究
- Author:
Huanqi GE
;
Hanqing CAI
;
Xiujuan ZHANG
;
Yanzhe ZHANG
;
Xuejun HUI
- Publication Type:Journal Article
- Keywords:
hyperthyroidism;
bone mineral density;
alkaline phosphatase;
calcium
- From:
Journal of Jilin University(Medicine Edition)
2000;26(6):612-614
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the effect of thyroid function on bone metabolism. Methods:Serum FT3,FT4 were investigated by radioimmunoassay (RIA) and bone mineral density of spine (L2～4) weremeasured by dual energy x-ray absorptinmetry and other markers related to bone metabolism were alsomonitored in 30 patients with hyperthyroidism and 30 healthy volunteers. Results :The levels of FT3,FT4,ALP were significantly higher than those of the normal controls. BMD of spine decreased significantly incomparison with the controls ,and the degree of severity and incidence increased with age. Conclusion:Thy-roid hormone might speed up bone turnover directly with increased bone resorption to induce bone massloss.
